Identification of Gonadotropin Surge-Inhibiting Factor (GnSIF) in Follicular Fluid and its Differentiation from Inhibin1
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چکیده
منابع مشابه
Marja-liisa Hendriks Purification of a Candidate Gonadotropin Surge-inhibiting/attenuating Factor (gnsif/af) Showing Mapk as a Possible Target
Gonadotropin surge-inhibiting/attenuating factor (GnSIF/AF) has been known for over two decades, but its molecular structure has not been completely characterized yet. In the last 20 years, five different putative GnSIF/AF sequences have been published. In this article, we describe a procedure to isolate and characterize GnSIF/AF from bovine follicular fluid. A GnSIF/ AF-derived synthetic pepti...
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the aim of the present study was to determine the in?uence of presence or absence of corpus luteum (cl) on hormonal and metabolites composition of follicular ?uid (ff) harvested from different sized follicles and its relationship with blood serum concentrations in sanjabi ewes. ovaries and blood samples were collected from 60 clinically healthy adult ewes (sanjabi breed) 1–3 years of age in dio...
Purification of a candidate gonadotrophin surge attenuating factor from human follicular fluid.
Gonadotrophin surge attenuating factor (GnSAF) is a new non-steroidal ovarian substance, different from inhibin, which attenuates the pre-ovulatory luteinizing hormone (LH) surge in superovulated women. Human follicular fluid (FF) was used as a source for the isolation of GnSAF, the activity of which was monitored in an in-vitro pituitary bioassay. Primary rat pituitary cells were incubated wit...
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15 صفحه اولSexual differentiation of the surge mode of gonadotropin secretion: prenatal androgens abolish the gonadotropin-releasing hormone surge in the sheep.
In sheep, the surge mode of gonadotropin secretion is sexually differentiated, i.e. the LH surge is present in the female, but not in the male. The present study tested the hypothesis that sexual differentiation of the LH surge mechanism reflects a sex difference in the pattern of GnRH, and that prenatal androgens abolish the surge mode of GnRH secretion. We monitored the pattern of GnRH secret...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 1987
ISSN: 0006-3363,1529-7268
DOI: 10.1095/biolreprod37.5.1075